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Micron sized beads can be trapped in regions of high light intensity. A laser
beam wavefront can be sculpted by a computer generated hologram and focused on
an almost arbitrary intensity distribution. We're working on applications of
holographic optical micro- manipulation to microfluidics, statistical
mechanics, colloidal science.
Life at the mesoscopic scale can be much different than our macroscopic world.
Fluids flow without inertia, liquid interfaces can be as hard as walls,
thermal agitation of the environment kicks so strongly that objects wander
around restlessly. We're interested in colloidal interactions, complex
rheology of suspensions, surface phenomena.
Thermal fluctuations drive dynamics on the meso and microscopic scales. Energy
provides the background landscape for the resulting motions. Using
experiments and computer simulations we look at both the single particle
Brownian motion in external force fields and the slow, cooperative relaxations
in glassy systems arising from highly complex multidimensional landscapes.
We work at the design of new light driven devices and sensors providing non -
invasive tools to manipulate and analyze micro - environments such as
microfluidic devices or biological samples.
We have demonstrated that the full power of holographic optical tweezers can be available
inside diamond anvil cells for high pressure studies in physics and biology.
Seeing and touching through an optical fiber
We have demonstrated that a single multimode optical fiber
can be used as a submillimiter probe for interactive
micromanipulation and fluorescence microscopy.
Lab on Chip review
Holographic optical tweezers and their relevance to lab on chip devices. A
Critical Review by Padgett and Di Leonardo for Lab on Chip journal.
Swimming with an image
E.coli bacteria can swim along straight lines, but in proximity to a water-air surface, the flows produced by its hydrodynamic image send it circling counterclockwise when viewed from above.
Hologram transmission through multimode fibers
Computer generated holograms can travel along multimode fibers
and produce dynamic light patterns on the other end.
Self-starting micromotors in a bacterial bath
Micromotors pushed by biological entities, constitute a fascinating way to
convert chemical energy into mechanical work at the micrometer scale. We show
that a properly designed asymmetric object can be spontaneously set into the
desired motion when immersed in a chaotic bacterial bath.
HOTs with CUDA
Using the highly parallel architecture of modern graphics card, optimized
holograms can be calculated iteratively in real time.